Comparison of Early and Interval Laparoscopic Cholecystectomy for Treatment of Acute Cholecystitis. Which is Better? A Multicentered Study.

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dc.contributor.author Turel, Kadir Serkan
dc.contributor.author Isik, Ozgen
dc.contributor.author Yilmaz, Nimet
dc.contributor.author Yilmaz, Fatih A
dc.contributor.author Uysal, Erdal
dc.contributor.author Sipahi, Mesut
dc.date.accessioned 2021-07-01T13:27:35Z
dc.date.available 2021-07-01T13:27:35Z
dc.date.issued 2016
dc.identifier.issn 1530-4515
dc.identifier.other 27846178
dc.identifier.uri https://doi.org/ 10.1097/SLE.0000000000000345 en_US
dc.identifier.uri http://openaccess.sanko.edu.tr/xmlui/handle/20.500.12527/316
dc.description.abstract The aim of this study was to compare early laparoscopic cholecystectomy (LC) and LCs performed at different time intervals for treatment of acute cholecystitis, contribute to the literature with data obtained from different centers, and provide assistance to clinicians about the timing of LC in acute cholecystitis. The study was designed as a retrospective, observational, and multicentered study. The data of 470 patients who had undergone LC for treatment of acute cholecystitis between January 2010 and March 2016 were included. Four different centers contributed to the study. The patients were divided into 4 groups. The groups were identified according to the timing of LC following the onset of findings and symptoms of acute cholecystitis as group 1 (first week), group 2 (1 to 4 wk), group 3 (4 to 8 wk), and group 4 (>8 wk). The clinical and demographical characteristics, comorbidities, complications, hospital stay, duration of operation, conversion rates, and rehospitalizations in the following 30 days of patients in the groups were compared. A significant increase was found in group 4 compared with groups 1 and 2 in relation to comorbidities (P<0.01) (P=0.042). No statistically significant difference was observed among the groups for the comparison of operation durations, conversion rates, and total number of complications (P>0.05). The groups were compared with regard to the mean hospital stay, and the hospital stay was found to be significantly higher in group 4 than in group 1 (P=0.001). In our study, the 30-day readmission rate was determined to be significantly higher in the >8-week group (group 4) compared with the first-week (group 1) and 1- to 4-week group (group 2) (P<0.05). Interval LC does not decrease the complication rate, conversion rate, or the operation time. Early LC could be preferred for treatment of acute cholecystitis as no significant differences related to the conversion rate, operation time, and overall complication rate are observed between the early and delayed LCs; however, a shorter hospital stay and lower 30-day readmission rate are observed in early LC for the treatment of acute cholecystitis. en_US
dc.language.iso English en_US
dc.publisher LIPPINCOTT WILLIAMS & WILKINS, TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.title Comparison of Early and Interval Laparoscopic Cholecystectomy for Treatment of Acute Cholecystitis. Which is Better? A Multicentered Study. en_US
dc.type Article en_US
dc.relation.journal SURGICAL LAPAROSCOPY ENDOSCOPY & PERCUTANEOUS TECHNIQUES en_US
dc.identifier.issue 6 en_US
dc.identifier.startpage 117 en_US
dc.identifier.endpage 121 en_US
dc.identifier.volume 26 en_US
dc.contributor.authorID 0000-0002-9541-5035 : Ozgen Isik en_US
dc.identifier.wos 000391108300004 en_US
dc.identifier.doi 10.1097/SLE.0000000000000345 en_US
dc.contributor.sankoauthor Erdal Uysal en_US
dc.contributor.sankoauthor Nimet Yılmaz en_US


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Gazimuhtar Paşa Bulvarı
No:36
27090
Şehitkamil / GAZİANTEP