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Fizyoloji Anabilim Dalı

Fizyoloji Anabilim Dalı

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Effect of Long-Term Centrally Injected Histamine and Its Receptors Antagonist on The Hypothalamic Cyclooxygenase and Lipoxygenase Enzymes in Rats

Baş, Ayşenur; Güvenç Bayram, Gökçen; Altınbaş, Burçin; Özyurt, Ebru; Yalçın, Ebru; Erbaykent Tepedelen, Burcu; Ersoy, Figen; Yalçın, Murat (2019)

The current study was designed to determine the effect of centrally chronic-administrated histamine and histaminergic receptors antagoniston the level of hypothalamic cyclooxygenase (COX) and lipoxygenase (LOX) enzymes.Studies ...
The mediation of central cyclooxygenase and lipoxygenase pathways in orexin-induced cardiovascular effects.

Altınbaş, Burçin; Güvenç Bayram, Gökçen; Yalçın, Murat (ELSEVIERRADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS, 2021-03-01)

Previously it was reported that central orexin (OX) and arachidonic acid (AA) signaling pathways played an active role in the control of the cardiovascular system. It was also reported that they have exhibited their ...
K channel blockage with 3,4-diaminopyridine potentiates the effect of L-DOPA on dopamine release in striatal slices prepared from 6-OHDA pre-treated rats.

Gul, Zulfiye; Duyu, Gozde; Altınbaş, Burçin; Buyukuysal, R Levent (SPRINGERONE NEW YORK PLAZA, SUITE 4600 , NEW YORK, NY 10004, UNITED STATES, 2020-11-01)

Although L-DOPA revolutionized in the treatment of Parkinson's disease, most patients developed motor complications after several years of treatment. Adjunctive therapy to L-DOPA with drugs related to dopaminergic signaling ...
Modulation of arachidonic acid-evoked cardiorespiratory effects by the central lipoxygenase pathway.

Güvenç, Bayram Gökçen; Altınbaş, Burçin; Erkan, Leman Gizem; Yalçın, Murat (ELSEVIERRADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS, 2020)

We previously reported that intracerebroventricularly (ICV) injected arachidonic acid (AA) could produce pressor and bradycardic responses on the cardiovascular system and hyperventilation effect on the respiratory system ...
Intracerebroventricularly injected nesfatin-1 activates central cyclooxygenase and lipoxygenase pathways.

Guvenc-Bayram, Gokcen; Altınbaş, Burçin; Iqbal, Awais; Cerci, Ece; Udum, Duygu; Yilmaz, Mustafa Sertac; Erdost, Hatice; Yalcin-Ulger, Ebru; Ilhan, Tuncay; Ersoy, Figen; Uz, Elif; Yalçın, Murat (ELSEVIERRADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS, 2020)

Nesfatin-1 is a multifunctional neuropeptide having crucial autonomic roles. It is well known that nesfatin-1 collaborates with other central neuromodulatory systems, such as central corticotropin-releasing hormone, ...
Contingent role of phoenixin and nesfatin-1 on secretions of the male reproductive hormones.

Guvenc, Gokcen; Altinbas, Burcin; Kasikci, Esra; Ozyurt, Ebru; Bas, Aysenur; Udum, Duygu; Niaz, Nasir; Yalcin, Murat (WILEY111 RIVER ST, HOBOKEN 07030-5774, NJ, 2019)

Phoenixin (PNX) and nesfatin-1 are localised in the hypothalamus and the pituitary gland. Moreover, the most of the PNX-expressing neurons in the hypothalamus also co-express nesfatin-1. These outcomes may suggest that ...
Effects of Acute Exhaustive Exercise on Oxidant and Antioxidant System Parameters in Rats with Streptozotocin Induced Diabetes Mellitus

Sahin, Ahmet Melih; Sonmez, Osman; Mengi, Murat; Altan, Mehmet; Toprak, Muhammed Sait; Ekmekci, Hakan; Metin, Gokhan; Cakar, Lutfi (WILEY111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2017)
The Effects of Reactive Oxygen Species and TRPA1 Receptors on Nociceptive Firing and Calcitonin Gene-related Peptide Release in Rat Meninges

Kilinc, Erkan; Tore, Fatma; Giniatullin, Rashid (WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2016)
The Role of Adenosine Triphosphate and its Receptors in Migraine Pathophysiology

Kilinc, Erkan; Koroleva, Kseniia; Toro, Cindy Guerrero; Tore, Fatma; Giniatullin, Rashid (WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2015)
Vasoactive Intestinal peptide modulates c-Fos activity in the trigeminal nucleus and dura mater mast cells in sympathectomized rats.

Kilinc, Erkan; Firat, Tülin; Tore, Fatma; Kiyan, Aysu; Kukner, Aysel; Tunçel, Nese (WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2015)

Neurogenic inflammation in the dura mater caused by trigeminal nociceptive activation has been implicated in the pathophysiology of migraine. Vasoactive intestinal polypeptide (VIP) is a powerful neuroprotective neuropeptide ...

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