dc.contributor.author | Yilmaz, Soner | |
dc.contributor.author | Unlu, Aytekin | |
dc.contributor.author | Cetinkaya, Riza Aytaç | |
dc.contributor.author | Yapar, Mehmet | |
dc.contributor.author | Avci, Ismail Yasar | |
dc.contributor.author | Yilmaz, Sebahattin | |
dc.contributor.author | Eyigun, Can Polat | |
dc.date.accessioned | 2021-06-25T07:21:34Z | |
dc.date.available | 2021-06-25T07:21:34Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 1473-0502 | |
dc.identifier.other | 26928919 | |
dc.identifier.uri | https://doi.org/ 10.1016/j.transci.2015.10.004 | en_US |
dc.identifier.uri | http://openaccess.sanko.edu.tr/xmlui/handle/20.500.12527/273 | |
dc.description.abstract | Screening of blood donations for antibodies against hepatitis B core antigen (anti-HBc) is used to prevent transfusion transmitted hepatitis B virus (HBV) infection. In this study, we studied the magnitude of blood donor gain by using a re-entry mechanism in our Blood Bank of Gulhane Military Academy of Medicine. Between January and May 2013, 5148 voluntary blood donors were screened by ELISA method for HBsAg, anti-HBc total and other screening markers, prospectively. Samples with repeated reactivity for the presence of anti-HBc were further tested with four supplemental assays. We detected 515 (10%) anti-HBc positive and 4612 (90%) anti-HBc negative cases in 5127 HBsAg negative serum samples. A total of 461 (89.5%) blood units were reactive for at least one additional serologic parameter and 54 were (10.5%) negative. Isolated anti-HBc positivity rate was 1.3% (69/5127). In the isolated anti-HBc positive samples, 54 were also anti-HBe and HBeAg negative. HBV DNA was not detected in any of the samples. Applying the EDQM criteria would decrease our blood donor loss from 10% to 5.4%. As alternative re-entry mechanisms have already been presented in the literature, institution of a new policy is needed to enhance the limited blood donor pool in our system. | en_US |
dc.language.iso | English | en_US |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Anti-HBc assays | en_US |
dc.subject | Anti-HBs | en_US |
dc.subject | Blood donor screening | en_US |
dc.subject | HBV DNA | en_US |
dc.subject | Transfusion-associated HBV | en_US |
dc.title | A strategical re-thinking on National Blood Donor Pool: Anti-HBc positivity related re-entry mechanisms. | en_US |
dc.type | Article | en_US |
dc.relation.journal | TRANSFUSION AND APHERESIS SCIENCE | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.startpage | 271 | en_US |
dc.identifier.endpage | 275 | en_US |
dc.identifier.volume | 54 | en_US |
dc.contributor.authorID | 0000-0002-3043-0664 : Aytekin Ünlü | en_US |
dc.contributor.authorID | 0000-0001-6210-4524 : Can Polat Eyigun | en_US |
dc.identifier.wos | 000377730900021 | en_US |
dc.identifier.doi | 10.1016/j.transci.2015.10.004 | en_US |
dc.contributor.sankoauthor | Can Polat Eyigün | en_US |
Files | Size | Format | View |
---|---|---|---|
There are no files associated with this item. |
Gazimuhtar Paşa Bulvarı
No:36
27090
Şehitkamil / GAZİANTEP