dc.contributor.author | Akgül, Ferit | |
dc.contributor.author | Serçelik, Alper | |
dc.contributor.author | Çetin, Hakan | |
dc.contributor.author | Erten, Turgay | |
dc.date.accessioned | 2021-07-29T07:14:41Z | |
dc.date.available | 2021-07-29T07:14:41Z | |
dc.date.issued | 2017 | |
dc.identifier.issn | 1932-6203 | |
dc.identifier.other | 29176783 | |
dc.identifier.uri | https://doi.org/ 10.1371/journal.pone.0188669 | en_US |
dc.identifier.uri | http://openaccess.sanko.edu.tr/xmlui/handle/20.500.12527/352 | |
dc.description.abstract | Previous reports about the relationship between a high parathyroid hormone (PTH) and low vitamin D levels with blood pressure in different hypertension groups are conflicting. We studied serum PTH and vitamin D levels in white-coat (WCHT) and sustained hypertension (SHT) patients who had not been on antihypertensive treatment. We also investigated the association between serum PTH and vitamin D levels with respect to blood pressure in SHT and WCHT patients. We included 52 SHT patients (54.06 ± 9.2 years, 32 newly diagnosed and 20 previously diagnosed with SHT who had not been treated with antihypertensive medication for 3 months or more), 48 WCHT patients (53.64 ± 9.5 years), and 50 normotensive (NT) healthy controls (53.44 ± 8.4 years) in our study. In addition to routine tests, PTH and vitamin D levels were measured. Serum PTH levels were significantly higher in SHT patients not taking antihypertensive medications than in WCHT patients and NT controls (p = 0.004). Although PTH levels were higher in WCHT than in NT groups, the difference was not statistically significant. In SHT patients, PTH levels showed a positive correlation with office systolic (r = 0.363, p = 0.008), office diastolic (r = 0.282, p = 0.038), home systolic (r = 0.390, p = 0.004), and home diastolic blood pressures (r = 0.397, p = 0.003). Serum vitamin D levels were similar in SHT, WCHT and NT groups. Vitamin D levels were not associated with blood pressures in the entire study group. Furthermore, no significant relation was found between vitamin D and PTH levels in SHT and WCHT groups. PTH levels are significantly higher in untreated SHT patients than WCHT patients and NT subjects. However, vitamin D levels are similar in SHT, WCHT and NT groups. There is a significant association between PTH levels and blood pressures suggesting PTH has a role in increase of blood pressure in SHT. | en_US |
dc.publisher | PUBLIC LIBRARY SCIENCE1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | BLOOD-PRESSURE | en_US |
dc.subject | INCIDENT HYPERTENSION | en_US |
dc.subject | CARDIOVASCULAR RISK | en_US |
dc.subject | 25-HYDROXYVITAMIN D | en_US |
dc.subject | PRIMARY HYPERPARATHYROIDISM | en_US |
dc.subject | INDEPENDENT ASSOCIATIONS | en_US |
dc.subject | MASKED HYPERTENSION | en_US |
dc.subject | GENERAL-POPULATION | en_US |
dc.subject | EUROPEAN-SOCIETY | en_US |
dc.subject | ATHEROSCLEROSIS | en_US |
dc.title | Association of parathyroid hormone and vitamin D with untreated hypertension: Is it different in white-coat or sustained hypertension? | en_US |
dc.type | Article | en_US |
dc.relation.journal | PLOS ONE | en_US |
dc.identifier.issue | 11 | en_US |
dc.identifier.volume | 12 | en_US |
dc.contributor.authorID | 0000-0002-1383-1001 : Ferit Akgül | en_US |
dc.identifier.wos | 000416291900113 | en_US |
dc.identifier.doi | 10.1371/journal.pone.0188669 | en_US |
dc.contributor.sankoauthor | Alper Serçelik | en_US |
Dosyalar | Boyut | Biçim | Göster |
---|---|---|---|
Bu öğe ile ilişkili dosya yok. |
Gazimuhtar Paşa Bulvarı
No:36
27090
Şehitkamil / GAZİANTEP