dc.contributor.author | Barut, Osman | |
dc.contributor.author | Seyithanoglu, Muhammed | |
dc.contributor.author | Kucukdurmaz, Faruk | |
dc.contributor.author | Demir, Bekir Turkay | |
dc.contributor.author | Olmez, Caner | |
dc.contributor.author | Dogan, Neslihan Temiz | |
dc.contributor.author | Resim, Sefa | |
dc.date.accessioned | 2021-10-20T17:25:33Z | |
dc.date.available | 2021-10-20T17:25:33Z | |
dc.date.issued | 2020-11-01 | |
dc.identifier.issn | 0303-4569 | |
dc.identifier.other | 32776559 | |
dc.identifier.uri | http://openaccess.sanko.edu.tr/xmlui/handle/20.500.12527/464 | |
dc.description.abstract | The aim of this study was to investigate the diagnostic value of serum G protein-coupled oestrogen receptor (GPER) levels and their correlation with semen parameters in men with infertility. The participants were divided into two groups as follows: 76 fertile control men (Group 1) and 77 infertile men (Group 2). Semen analysis, hormonal evaluation, serum GPER level and scrotal ultrasound of the participants were evaluated. Follicle-stimulating hormone and total testosterone levels were not significantly different between the groups (p = .413 and p = .535 respectively). The oestradiol level in Group 1 was significantly lower than that in Group 2 (p < .001). The serum GPER level was found to be significantly higher in Group 1 than that of Group 2 (p < .001). GPER levels were positively correlated with the total sperm count, sperm concentration, motility and morphology in Group 2 (r = 0.303, 0.345, 0.260 and 0.322, respectively, p < .001). In this study, GPER levels were positively correlated with sperm parameters, and it was hypothesised that the decrease in GPER expression might be associated with male infertility by adversely affecting spermatogenesis. | en_US |
dc.language.iso | English | en_US |
dc.publisher | WILEY111 RIVER ST, HOBOKEN 07030-5774, NJ | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | G protein-coupled oestrogen receptor | en_US |
dc.subject | infertility | en_US |
dc.subject | male | en_US |
dc.subject | oestradiol | en_US |
dc.subject | spermatogenesis | en_US |
dc.title | Relationship between the G protein-coupled oestrogen receptor and spermatogenesis, and its correlation with male infertility. | en_US |
dc.type | Article | en_US |
dc.relation.journal | ANDROLOGIA | en_US |
dc.identifier.issue | 10 | en_US |
dc.identifier.volume | 52 | en_US |
dc.contributor.authorID | 0000-0002-8296-9717 : Osman Barut | en_US |
dc.identifier.wos | 000557678500001 | en_US |
dc.identifier.doi | 10.1111/and.13779 | en_US |
dc.contributor.sankoauthor | Faruk Küçükdurmaz | en_US |
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Gazimuhtar Paşa Bulvarı
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27090
Şehitkamil / GAZİANTEP