Apoptotic Effect of Haplophyllum Buxbaumii Extract on Prostate Cancer

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dc.contributor.author Kazımoğlu, Hatem
dc.contributor.author Kaplan, Halil Mahir
dc.date.accessioned 2021-12-23T08:34:15Z
dc.date.available 2021-12-23T08:34:15Z
dc.date.issued 2020
dc.identifier.issn 2146-9954
dc.identifier.uri http://openaccess.sanko.edu.tr/xmlui/handle/20.500.12527/683
dc.description.abstract Prostate cancer is a common type of cancer amongmen. Recently, studies on new anticancer agents ofherbal origin in the treatment of cancer haveincreased. Haplophyllum buxbaumii (HP) is aperennial herbaceous plant. Studies have reported thatHaplophyllum subspecies has antioxidant properties.And the anticancer effect of HP is unknown. Thisstudy aims to reveal the apoptotic effect HP onprostate cancer. The cytotoxic effect of HP wasevaluated by the MTT method. In addition, apoptoticpathway mediators were analyzed by ELISA method.HP extract application reduced the viability ofprostate cancer and activated the apoptotic mediatorswhile decreasing anti-apoptotic mediators. Our studyshowed that HP extract has an antiproliferative andapoptotic effect on prostate cancer. en_US
dc.language.iso English en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.title Apoptotic Effect of Haplophyllum Buxbaumii Extract on Prostate Cancer en_US
dc.type Article en_US
dc.relation.journal Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi en_US
dc.identifier.issue 3 en_US
dc.identifier.startpage 267 en_US
dc.identifier.endpage 271 en_US
dc.identifier.volume 9 en_US
dc.contributor.authorID 0000-0001-8224-5068 : Hatem Kazımoğlu en_US
dc.contributor.sankoauthor Hatem Kazımoğlu en_US


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Gazimuhtar Paşa Bulvarı
No:36
27090
Şehitkamil / GAZİANTEP