Apoptotic Effect of Haplophyllum Buxbaumii Extract on Prostate Cancer

Kazımoğlu, Hatem; Kaplan, Halil Mahir

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dc.contributor.author	Kazımoğlu, Hatem
dc.contributor.author	Kaplan, Halil Mahir
dc.date.accessioned	2021-12-23T08:34:15Z
dc.date.available	2021-12-23T08:34:15Z
dc.date.issued	2020
dc.identifier.issn	2146-9954
dc.identifier.uri	http://openaccess.sanko.edu.tr/xmlui/handle/20.500.12527/683
dc.description.abstract	Prostate cancer is a common type of cancer amongmen. Recently, studies on new anticancer agents ofherbal origin in the treatment of cancer haveincreased. Haplophyllum buxbaumii (HP) is aperennial herbaceous plant. Studies have reported thatHaplophyllum subspecies has antioxidant properties.And the anticancer effect of HP is unknown. Thisstudy aims to reveal the apoptotic effect HP onprostate cancer. The cytotoxic effect of HP wasevaluated by the MTT method. In addition, apoptoticpathway mediators were analyzed by ELISA method.HP extract application reduced the viability ofprostate cancer and activated the apoptotic mediatorswhile decreasing anti-apoptotic mediators. Our studyshowed that HP extract has an antiproliferative andapoptotic effect on prostate cancer.	en_US
dc.language.iso	English	en_US
dc.rights	info:eu-repo/semantics/openAccess	en_US
dc.title	Apoptotic Effect of Haplophyllum Buxbaumii Extract on Prostate Cancer	en_US
dc.type	Article	en_US
dc.relation.journal	Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi	en_US
dc.identifier.issue	3	en_US
dc.identifier.startpage	267	en_US
dc.identifier.endpage	271	en_US
dc.identifier.volume	9	en_US
dc.contributor.authorID	0000-0001-8224-5068 : Hatem Kazımoğlu	en_US
dc.contributor.sankoauthor	Hatem Kazımoğlu	en_US